Most readers don't read. They scan, sweep, and skip. Eye-tracking studies done since the early 2000s have repeatedly shown a particular pattern in how people consume web pages: an F-shape, almost like a column with one or two horizontal beams across it.
The top beam is the strongest signal. Readers see your headline, your navigation, and the first sentence of your hero. If those don't earn their attention, the rest of the page is at risk.
Where the eye drifts next
After the top sweep, the eye drops down a few lines and makes a shorter horizontal pass. This is where second-level headlines, lead sentences, and pull quotes live. Put a strong sub-headline here and your scanner becomes a reader.
From there, attention slides down the left margin, sipping the first few words of each line. The right side of the screen, sadly, is often invisible.
What to do about it
Left-align almost everything. Place your call-to-action at the start of a line, not the end. Make sure the first 3-5 words of each paragraph carry meaning. Bold the lead sentence of long blocks. And don't waste the right rail — make it a table of contents, a sticky CTA, or a related link.
Design for scanners first; the readers will take care of themselves.